I’m seeing a couple possibilities here for a overnight paddle and camp trip. The first one is just heading straight down the main body of the Santee river starting at Jamestown, SC.

Day 1: Echaw Creek-McConnell’s Landing

Day 2: McConnell’s Landing – Wambaw Creek (via Chicken Creek)

According to the available info both segments are about 4-5 hours paddling time. That will leave us time to stop and fish along the way and not be in a rush to get to the landing. Also, the entire southern bank is national forest land. Several more landing spots not on the map are available for camping/stopping.

Map link

Jamestown-Santee river:

https://berkeleyblueways.com/2017/10/13/jamestown-santee-river/

https://www.sctrails.net/trails/trail/jamestown-santee-river

 

The other possibility is starting in a tributary to the river, but ending up in the same place.

Wambaw Creek:

Click to access stelprd3796939.pdf

https://www.sctrails.net/trails/trail/wambaw-creek

https://paddling.com/paddle/trips/wambaw-creek-francis-marion-national-forest-south-carolina/?lat=33.1775&lng=-79.4970&zoom=14

WARNING: THIS VIDEO CONTAINS QUESTIONABLE MUSIC CHOICES

Echaw Creek:

https://berkeleyblueways.com/2016/07/19/echaw-creek/

https://www.sctrails.net/trails/trail/echaw-creek

Click to access stelprdb5346213.pdf

Chicken Creek:

https://berkeleyblueways.com/2016/07/19/chicken-creek/

Click to access chicken-creek-map.pdf